Heparin prevents programmed cell death in human trophoblast

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Heparin prevents programmed cell death in human trophoblast.

Heparin is used clinically for the prevention of pregnancy complications associated with prothrombotic disorders, especially antiphospholipid antibody syndrome. Recent studies have suggested that heparin may exert direct effects on placental trophoblast, independently of its anticoagulant activity. We now demonstrate that heparin abrogates apoptosis of primary first trimester villous trophoblas...

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ژورنال

عنوان ژورنال: Molecular Human Reproduction

سال: 2006

ISSN: 1360-9947,1460-2407

DOI: 10.1093/molehr/gal026